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KMID : 0360319860180010029
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Journal of Korean Cancer Research Association
1986 Volume.18 No. 1 p.29 ~ p.34
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Clinical Significance of Serum Ferritin Determination in the Diagnosis of Primary Hepatocellular Carcinoma
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유재화/Ryu, Jae Hwa
양상호/박요한/구자영/박병채/Yang, Sang Ho/Park, Yo Han/Koo, Ja Young/Park, Byung Chae
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Abstract
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In an attempt to verify the possibility that serum ferritin and serum ferritin/transaminases ratio might be an useful marker in the diagnosis of primary hepatocellular carcinoma, we checked serum ferritin level as well as serum ferritin/transaminases ratio in 52 patients with chronic liver diseases including primary hepatocellular carcinoma.
Serum ferritin level in patients with liver cirrhosis (281±4.83㎍/L, mean±SE) and with hepatocellular carcinoma(321±29.73 ㎍/L, mean±SE) were significantly(p<0.0005) elevated in comparison to normal control group(78.33±4.24 ㎍/L, mean±SE), but no statistical significance was observed between the patient groups of liver cirrhosis and hepatocellular carcinoma.
Moreover, we also failed to observe. a significant difference of serum ferritin/transaminases ratio in patients with liver cirrhosis (8.30±1.63, mean±SE) and with hepatocellular carcinoma(8.46±1.62, mean±SE).
The results of this study, therefore, would indicate that serum . ferritin determination seems to be not helful in the differential diagnosis of primary hepatocellular carcinoma.
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